LA MARQUE

Les mécanismes du vieillissement Phytothérapie – No 2 : 53-56, Springer 2005
P. Lutzler, M. Khoualelene, K. Bekov, N. Lapalus, V. Carlien, P. Hutzler
https://link.springer.com/article/10.1007/s10298-005-0069-y
Shortenedtelomerelenghtisassociatedwithincreasedrisk of can : a meta-analysis
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020466
Telomeredysfunctionincreases mutation rate and genomicinstability
JA Hackett – August 2011
https://www.ncbi.nlm.nih.gov/pubmed/11509177
Chromothripsis and KataegisInduced by Telomere Crisis
J. Maciejowski – Decembre 2015
https://www.ncbi.nlm.nih.gov/pubmed/26687355
Fossel, MCells, Aging and Human Disease
Oxford UniversityPress 2004
https://global.oup.com/academic/product/cells-aging-and-human-disease-9780195140354?cc=fr&lang=en&
A naturalproductTelomeraseActivator as part of a health Maintenance program
Calvin B. Harley, Weimin Liu, Maria Blasco, Elsa Vera, William H. Andrews, Laura A.Briggs and Joseph M. Raffaele
https://www.liebertpub.com/doi/10.1089/rej.2010.1085
The TelomeraseActivator TA-65 elongates short telomeres and increaseshealthspan of adultoldmicewithoutincreasing cancer incidence
Bruno Bernardes de Jesus, Kerstin Scheeberger, Elsa Vera, AguedaTejera, Clavin B. Harley and Maria A. Blasco
https://www.ncbi.nlm.nih.gov/pubmed/21426483
Telomerasereactivation reverses tissue degeneration in agedtelomerasedeficientmice
Marie/a Jaskelioff, Florian L.Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrews C.Adams, Ergun Sahin, Maria Kost-Alimova, AfexeiProtopopov, Juan Cadinaos, James W.Horner, EleftheriaMaratos-Flier& Ronald A. OePinho.
Nature Volume 49, 102-106 January201;published online 28 november 2010.
https://www.nature.com/articles/nature09603?page=13
The ‘corepathway’ of aging
by Bill Schal/er Dana-Farber, Cancer lnstitute Communications.
https://news.harvard.edu/gazette/story/2011/02/the-core-pathway-of-aging/
ShorteningTelomeres Cause Problems
Association betweentelomerelength, specific causes of death, and years of healthy lite in health, aging and body composition, a popular-basedcohortstudy
Njajou OT, Hsueh WC, Blackburn EH, Newman AB, Wu SH, UR, Simonsick EM, Harris TM, Cummings SR, CawthonRM; for the healt ABC study – 2009
https://www.ncbi.nlm.nih.gov/pubmed/19435951
Telomerelengh, stem cells and aging
Maria A Blasco, Telomeres and Telomerase Group, MofecularOncology Program, Spanish National Cancer Centre Madrid, Spain, Published online 17 september 2007.
Nature Chemical Biology 2007.38.
https://www.nature.com/articles/nchembio.2007.38
Telomereshortening and aging
H.Z Jiang, Z. Ju, KL Rudolph, Z GerontolGeriat40:314-324;2007
https://www.ncbi.nlm.nih.gov/pubmed/17943234
LeukocyteTelomerelength and cardiovasculardisease in the cardiovascularhealthstudy
Annette L.Fitzpatrick, Richard A.Kronmal, Jeffrey P.Gardner, Bruce M.Patsy, Nancy S.
Jenny, Russel P. Tracy, Jeremy Waltson, Masyuki Kimura, Abraham Aviv, American Journal of Epidemiology207; 165: 14-21.

https://academic.oup.com/aje/article/165/1/14/232589
AcceleratedTelomere Erosion ls associatedwith a declining immune function ofcaregivers of Alzheimer’sdisease patients.
Amanda K. Damjanovic, Yinhua Yang, Ronald Glaser, Janice K.Kiecolt-Glaser, Huy Nguyen, Bryon Laskowski, Yixiao Zou, David O. Beversdorf and Nan-PingWeng. The journal of
lmmunology 2007 179:4249-4254.

https://www.jimmunol.org/content/179/6/4249.short
Evidence thataging and amyloidpromotemicroglialcell senescence
Barry E. Flanary, Nicole W.Sammons, Cuong Nguyen, Douglas Walker and Wofgang J. Streit. Rejuvenationresearch Volume 10 number 1 2007
https://www.ncbi.nlm.nih.gov/pubmed/17378753
Telomere and Telomerase in stem cells (2007)
E. Hiyamaang K Hiyama, British Journal of Cancer (2007) 96, 1020-1024 .
https://www.ncbi.nlm.nih.gov/pubmed/17353922
Cellaging in relation to stress arousal and cardiovasculardiseaseriskfactors
Epel ES, Un Wl1helm FH, Wolkowitz OM, Cawthon R_, Adler NE, Oolbter _ C, Mendes WB, Blackburn EH. Psychoneuroendocrinology 2006 Apnl ;31 (3) : 277-87.
https://dash.harvard.edu/bitstream/handle/1/3128692/Mendes_CellAgingRElation.pdf
Telomerasetherapeutics for degenerativeDiseases
Calvin B. Harley, Pg o. Geron Corporation, 230 Constitution Drive, Menlo Park, CA USA 94025 HCurrentMolecularMedicine, 2005 .
https://www.ncbi.nlm.nih.gov/pubmed/15974874
Telomeres and the Immune System :Telomerase-based Pharmacologie Enhancement of Antiviral Function of Human CDS+ T Lymphocytes1 (2008)
Steven Russel Fauce, BethD.Jamieson, Allison C.Chin, Ronald T.Mitsuyasu, T.Parish,Hwee L. NG,
Department of Pathology and LaboratoryMedicine and Department of Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles CA 90095;Geron, MenloPark, Ca 94025; and department of Biostatistics, University of California-Los Angeles, School of Public Health, Los Angeles, CA 90095
The Journal of lmmunology 2008, 181, 7400-7406.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682219/
Telomerase-basedapproaches to enhanceimmunity to virusesduringageing (2007)
Rita EftrosPresentationSummary for SENS (Aubrey de Grey) Conference 6 sept.2007
B Effros, David Geffen School of Medicine at UCLA, Department of pathology and LaboratoryMedicine 10833 Le Conte Avenue, Los Angeles CA 90095-1732, USA.

https://www.lifespan.io/news/undoing-aging-with-aubrey-de-grey-part-three/
Telomerase induction in Tcells : A cure for Aging and desease?
Rita B.Effros, ExperimentalGerontology, Volume 42, Issue 5, May 2007, 416-420
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913844/
Telomeres and CardiovascularHealth
Role of telomeres in vascular senescence (2008).
Minamino T, Komuro/:Department of Cardiovascu/ar Science and Medicine Chiba UniversityGraduate of Medicine, 1-8-1 Front. Biosci. 2008 Jan 1; 13 : 2971-9

https://pdfs.semanticscholar.org/9ab1/d8d99c36d76633e818f9d96768341614e931.pdf
Telomeredysfunction in hypertension (2007)Study (2007)
Telomeredysfunction in hypertension (2007)Study (2007)
https://www.ncbi.nlm.nih.gov/pubmed/17921808
Telomerelengh in human naturel killer cellsubsets
https://www.ncbi.nlm.nih.gov/pubmed/17303822
Cellaging in relation to stress arousal as cardiovasculardiseaseriskfactors.
Epel ES, Un J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, Dolbter C, Mendes WBlackburn EH. Psychoneuroendocrinology 2006 Apr; 31 (3):277-87;
https://www.sciencedirect.com/science/article/abs/pii/S0306453005001897
Acceleratedtelomereshortening in response to lite stress
ElissaS.Epel, Bisabeth H. Blackburn. Jue Lin, Firdaus S Dhabhar, Nancy E. Adler, Jason D Morro1v and Richard M. Cawthon PNAS December 7 2004 vol. 101 N° 49 17312-17315 .
https://www.pnas.org/content/101/49/17312.short
A two-step mode for senescence triggered by a single critically short telomere
Pauline Abdallah, Pierre Luciano, Kurt W. Runge, Michael Lisby, Vincent Ge/y, Eric Gilson and M. Theresa Teixeira. Nature CellBiology 1, 988-93 (2009) .
https://www.ncbi.nlm.nih.gov/pubmed/19597486
Telomeres, cancer and aging : altering the humanlifespan
Fosse/ M. Banks D. JAMA 278 : 1345-1348; 1997.
https://jamanetwork.com/journals/jama/article-abstract/418445
Telomerase and the agingcell : Implications for humanhealth
Fosse/ M.JAMA 279: 1732-1735;1998
https://jamanetwork.com/journals/jama/article-abstract/187604
Association betweenTelomerelength, specific cases of death, and years of healthy litein health, aging and body composition, a population basedcohortstudy (2009).
Njajou OT, Hsueh WC, Blackburn EH, Newman AB, Wu SH, UR, Simonsick EM, Harris TM, Cummings SR, Cawt_honRM; for the hea/th ABC study.
https://academic.oup.com/biomedgerontology/article/64A/8/860/666405
Share environmentalfactorsassociatedwithtelomerelength maintenance in elderlymaletwins
NazmulHuda, Hiromi Tanaka, Brittney-Shea Herbert, Terry Reed and David Gilley.
Department of Medical and MolecularGenetics, Indiana UniversitySchool of Medicine, Indianapolis, IN 46202 USA. AgingCell 200

https://onlinelibrary.wiley.com/doi/full/10.1111/j.1474-9726.2007.00330.x
Cellular Senescence : whenbadthingshappen to good cells.
Judith Campis and Fabrizio d’Adda Di Fagagna : Nature Reviews / MolecularCel/ Biology Volume BI September 2007/729.
https://www.nature.com/articles/nrm2233
Telomeres : Cancer to Human Aging
Sheila A. Stewart/ and Robert A. Weinberg 2
https://www.annualreviews.org/doi/abs/10.1146/annurev.cellbio.22.010305.104518
Telomerelength in different tissues of elderly patients (2000)
Friedrich U., Griese E, Schwab M, Fritz P, Thon K, Klotz U MechAgeing Dev 2000 15:89-9
https://www.sciencedirect.com/science/article/abs/pii/S0047637400001731
Paper RecastAlzheimer’s As Cardiovasculardisorder (2007)
The Telomère-Telomerase axis and the heart (2007)

Kajstura J., Rota M, Urbanek K, Hosoda T, Cardiovascu/arResearchlnstitute, Department of Medicine, New York Medical Col/ege, Va/ha/la, New York 10595, USA
Antioxydants & Redox Signaling. November 2006 8(11-12): 2125-2141.

https://www.liebertpub.com/doi/abs/10.1089/ars.2006.8.2125
Telomerelength and replicative aging in humanvascular tissues (1995)
Edwin Chang and Calvin B. Harley: Proc. Nat!. Acad. Sei. USA Vol 92, pp 11190-11194, November 1995 Cel/ Biology.
https://www.pnas.org/content/92/24/11190.short
Telomeres and Cancer
Tumor-inducedSenescent T CellswithSuppressorFunction : A potentialform of tumor immune evasion (2008)
Carolina L.Montes, Andrei I.Chapoval, Jonas Nelson, VbenosaOrhue- Cancer Research 2008;68(3):870-9.

https://cancerres.aacrjournals.org/content/68/3/870.short
Fish-ing for links between cancer and aging (2007)
Jan Karlseder, Ph O. assistant professor in Salk’sRegulatoryBiologyLaboratory, assisted by graduatestudent Colleen Naeger in the Kar/seder /ab and Anna Jauch.
https://www.salk.edu/news-release/fish-ing-for-links-between-cancer-and-aging/
Telomeredysfunction : A potentiel Cancer predisposition Factor
J National Cancer lnst. 2003 Aug20;95 (16)1211-18 Wu X.
https://academic.oup.com/jnci/article/95/16/1211/2520390
Telomeraseis not an oncogene (2002)
Calvin B.Harley, Geron Corporation, Menlo Park, CA 94025, USA Oncogene 21 :494-502, 200
https://www.ncbi.nlm.nih.gov/pubmed/11850774